Like sands through the hourglass
Impermanence is a fact of life. At least this 3D reality of being “human” at this particular moment in time anyway.
The smarter ones among us learn to use their awareness of it as fuel while sadly others, often either stay woefully blind to, or neurotically anxious of, time slipping away. Regardless, both cause stagnancy towards goals and a lack of peace in the process.
The meaning of life
What is the meaning of life? “My doctrine says: the task is to live in such a way that you must wish to live it again.” - Nietzsche